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Symbol
Name
ID
Tlr4
toll-like receptor 4
MGI:96824
Phenotype annotations related to digestive/alimentary system
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Intestinal obstruction
Constipation
Chronic constipation
Diarrhea
Nausea and vomiting
Vomiting
Gastrointestinal infarctions
Crohn's disease
Hepatocellular carcinoma
Disease(s) Associated with TLR4
familial mediterranean fever
hepatocellular carcinoma
temporal arteritis

Mouse Phenotypes
rectal hemorrhage
abnormal intestinal goblet cell morphology
abnormal enterocyte differentiation
abnormal enterocyte proliferation
digestive/alimentary phenotype
abnormal cecum morphology
enlarged cecum
Availability Mouse Genotype
Tlr4Lps-d/Tlr4Lps-d
Tlr4lps-del/Tlr4lps-del
Tlr4tm1.1(KOMP)Vlcg/Tlr4tm1.1(KOMP)Vlcg
Tlr4tm1.1Djh/Tlr4tm1.1Djh
Tlr4tm1Aki/Tlr4tm1Aki *
Tlr4tm1Djh/Tlr4tm1Djh
Tg(Vil1-cre)997Gum/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory